Throughout Wickersham's lengthy Instagram post, she doesn't mention anything about why she chose to leave after Season 18 of "NCIS." The most likely explanation is that she merely wanted to pursue other opportunities after playing the same character across eight seasons and 172 episodes. She can be a part of many projects now that she isn't regularly filming "NCIS," but what's most important is that it appears as though she left on good terms with everyone she worked with over the last decade.
As she mentions on Instagram, "I've been lucky enough to be a part of a show where I got to show up and act and laugh and learn with wonderful people. A moment in time I surely won't forget. Thank you CBS and NCIS for including me in a part of television history." As you go down her post, a slew of comments has already come in, including one from the official CBS Instagram account, which writes, "Thanks for making history with us." Wickersham's co-stars, including Maria Bello and Brian Dietzen, also use their accounts to express their pleasure of getting to work with her for so many years.
Wickersham's now free to pursue whatever projects interest her the most from here on out. While it's still unclear where she'll end up, bright things are inevitably in-store for the talented actress.