Of the four main kid characters on South Park, three of them — Stan, Kyle, and Kenny — live in two-parent homes with their mothers and fathers and at least one sibling, each under one roof. Eric Cartman's family setup is a little different, but it still seems like a run-of-the-mill one. He lives with his mother, Liane Cartman, and his father (or a father figure) is never in the picture. However, while you'll find a lot of families like that across America, the Cartman family is still, well, rather unique.
For many years, South Park explained that Eric Cartman's mother possessed both sets of reproductive organs, and that she was technically his father. But then the show revealed that Liane is, in fact, the character's mother, and she'd gotten pregnant after an affair with former Denver Broncos player and South Park resident Jack Tenorman.
But wait, Eric Cartman's lineage gets even more complicated. As it turns out, he had a live-in dad and a sister at one point. The unaired pilot of South Park is essentially the 1997 debut episode "Cartman Gets an Anal Probe," but it contains some footage that was deleted prior to its airing on Comedy Central. Among the excised material is a scene at the Cartman family dinner table, which includes Eric, Liane, and an unnamed Cartman father and Cartman sister. The characters were cut from the pilot, and they never appeared on South Park again.