If you ask a typical Arrested Development fan what they know about Lucille, they'll probably mention two things: her frequent drinking, and her love of winking. Lucille is pretty much always spotted with a drink in her hand, whether it's a martini or "breakfast wine," and her tolerance — and misguided beliefs — are legendary. Just before a drinking contest against George Sr.'s former assistant and lover Kitty (Judy Greer), Lucille takes an inaugural shot before announcing that it "didn't count," and Michael and Lindsay frequently discuss some of Lucille's beliefs, including that you have to finish a bottle of vodka once you open it, or it "goes bad." (As Michael tells Lindsay, "I think that's another one of Mom's fibs.")
As for her winking habit, Walter found the funniest possible way to wink, slowly lowering one eyelid at a weirdly glacial pace while keeping the other one open wide. This singular talent gets used a lot during the series, and sometimes even coincides with drinking, like in a scene where Lucille mistakes a symbol on a bottle of medication that means the pills could cause drowsiness and winks right back at it before downing a drink.
You can watch all of Lucille Bluth's moments on Arrested Development, which is streaming on Netflix now.